This high density C8 phase based on high purity NUCLEODUR silica gel with its endcapping suppresses any unwanted polar interactions between the silica surface and the sample, which makes “Gravity” particularly suitable for the separation of basic and other ionizable analytes. Due to the enhanced pH stability, LC/MS suitability and superior base deactivation (BDS) it is a perfect choice for method development and valuable for RP applications.
Hazardous material | No |
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Brand | NUCLEODUR |
Method | HPLC, analytical |
Phase | NUCLEODUR C8 Gravity |
Base material | NUCLEODUR - high purity silica |
Surface chemistry | Base deactivated (BDS), High density monomeric octyl (C8, MOS) modification |
Mode | Reversed phase (RP) |
Hardware | Stainless steel |
Type | EC HPLC column (analytical) |
USP listing | L7 |
Column length | 250 mm |
Column inner diameter | 4.6 mm |
Particle size | 5 µm |
Particle type | Fully porous particles (FPP) |
Particle shape | Spherical |
Pore size | 110 Å |
pH stability | 1.0–11.0 |
Carbon content | 11.0 % |
Endcapped | Yes |
Specific surface according to BET | 340 m²/g |
Pressure stability (max) | 600 bar |
Pore volume | 0.9 mL/g |
Eluent in HPLC column | Acetonitrile – water |
Recommended application | Analgesics, Antidepressants, Antiinflammatory drugs, Applications at pH extremes (1-11), Decreased retention of non-polar compounds, Herbicides, Ideal for method development, Immunosuppressants, Pharmaceuticals, Phytopharmaceuticals, RP applications HPLC, Similar to NUCLEODUR C18 Gravity, Suitable for LC-MS |
Temperature stability (max) | 60 °C |
Tmax (phosphate buffer) | 40 °C |
Column volume | 4.15 mL |
Scope of delivery | 1x analytical HPLC column, instruction leaflet, certificate of analysis |
Storage temperature | RT |
Catalog: https://www.mn-net.com/media/pdf/51/5e/04/Catalog-Chromatography-EN.pdf