How to find the right column as USP L code requirement

For USP L code requirement could follow below guide to help find out some famous LC column brand from many manufacture:

  1. https://www.gimitec.com/node/1480954

  2. Follow guide from: https://www.hplc.eu/Downloads/USP_HPLC_Packings.pdf

  3. HPLC Column database at: http://www.hplccolumns.org/database/index.php

  4. Some useful link refer from hplc.eu (https://www.hplc.eu/brands.htm)

Downloads
 The Chromatography and Sample Preparation Terminology Guide

 Five Keys to Successful LC Methods

 USP HPLC Packings

 NIST SRM 870: Column Performance Test Mixture for Liquid Chromatography

 HPLC Column Selection - Are You Barking Up the Right Tree?

 HPLC Column Classification - USP - Stimuli to the Revision Process

 ACD Column Selector - the six chromatographic column parameters

 SFC test for an extended ODS HPLC column classification (Article 1)
 SFC test for an extended ODS HPLC column classification (Article 2)
 SFC test for an extended ODS HPLC column classification (Article 3)
     This test provides, from a single analysis of carotenoid pigments, the absolute hydrophobicity, the silanol activity and the steric separation factor of the ODS stationary phases.


Useful links
HPLC Column Classification System (Katholieke Universiteit Leuven)
     More than 80 different types of ODS columns were characterized by 4 column parameters, which can be determined with 3 simple, fast, repeatable and reproducible chromatographic methods.
The Test Procedure (Katholieke Universiteit Leuven)

www.hplccolumns.org
http://www.hplccolumns.org/database/compare.php
     This website is a a free, online resource for selectivity data and tools for High Performance Liquid Chromatography. The current database contains column parameters for over 500 reversed-phase HPLC columns characterized using the Hydrophobic Subtraction Model of reversed-phase selectivity.

U.S. Pharmacopeia Column Equivalency Database
     The USP Database was developed by the USP Working Group on Column Equivalency using the NIST SRM 870. All data being displayed was generated by the column manufacturers after evaluation of the chromatographic phase.

ACD Column Selector (runs within the chemical drawing tool ACD ChemSketch Freeware)
     The columns are evaluated by 6 parameters (ligand density, hydrophobic sensitivity, shape selectivity, hydrogen bonding capacity, and total and acidic ion-exchange capacity). Since each parameter can be targeted individually, chromatographers can also search for columns that have high coefficients for a certain term, allowing them to change their columns to target a given structural aspect.

USP-NF Chromatographic Columns Online Database
The Chromatographic Columns online database is a compilation of the chromatographic columns used to validate the chromatographic procedures in USP–NF, Pharmacopeial Forum, Revision Bulletins, and Interim Revision Announcements. It provides a cumulative listing of columns referenced in gas and liquid chromatographic methods related to revisions made to USP–NF since January 1980.
Access
Chromatographic Columns, previously a print publication, is now a free, online database. To begin using the database, a one-time registration is required.  Also, after log in, Terms of Use must be agreed to before proceeding to the data.
     Register
     Login

www.chemicalize.org
This site was developed and is maintained by CHEMAXON (www.chemicalize.org) and contains most of the useful measurements that we need to help us understand analyte behaviour of a wealth of common, and some not so common, species.

MarvinSketch
A chemical structure drawing program containing some free plug-ins that can estimate/calculate physicochemical parameters of compounds.

Useful free tools for HPLC method development

Follow Guideline from Chiral Technologies, Daicel:

Downloads from https://www.hplc.eu/brands.htm

The Chromatography and Sample Preparation Terminology Guide

Five Keys to Successful LC Methods

USP HPLC Packings

NIST SRM 870: Column Performance Test Mixture for Liquid Chromatography

HPLC Column Selection - Are You Barking Up the Right Tree?

HPLC Column Classification - USP - Stimuli to the Revision Process

ACD Column Selector - the six chromatographic column parameters

SFC test for an extended ODS HPLC column classification (Article 1)
SFC test for an extended ODS HPLC column classification (Article 2)
SFC test for an extended ODS HPLC column classification (Article 3)
This test provides, from a single analysis of carotenoid pigments, the absolute hydrophobicity, the silanol activity and the steric separation factor of the ODS stationary phases.

USP and EP allowable adjustments
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